CONGENITAL DIABETES IN AN INFANT WITH TRISOMY-21

Authors
SHEHADEH N GERSHONIBARUCH R ETZIONI A
Citation
N. Shehadeh et al., CONGENITAL DIABETES IN AN INFANT WITH TRISOMY-21, Journal of pediatric endocrinology & metabolism, 11(4), 1998, pp. 575-576
Citations number
8
Categorie Soggetti
Pediatrics,"Endocrynology & Metabolism
Journal title
Journal of pediatric endocrinology & metabolism → ACNP
ISSN journal
0334018X
Volume
11
Issue
4
Year of publication
1998
Pages
575 - 576
Database
ISI
SICI code
0334-018X(1998)11:4<575:CDIAIW>2.0.ZU;2-3
Abstract
A newborn infant with trisomy 21 was found to have congenital diabetes which appears to be permanent. Congenital diabetes is extremely rare and differs from type I or type II diabetes. It has never been reporte d previously in Down's syndrome and it seems to be due to a selective beta cell defect with undetectable C-peptide but normal alpha-cell fun ction.