RECURRENCE OF BLACKWATER FEVER - TRIGGERING OF RELAPSES BY DIFFERENT ANTIMALARIALS

Five cases of blackwater fever (BWF) are described, all of whom had a history of recent quinine therapy In two cases a second haemolytic cri sis was induced by halofantrine, in one case also a third. increasing frequency of this syndrome with its dramatic clinical presentation is to be expected as imported P. falciparum infection, parasite resistanc e to chloroquine and the use of quinine and other related antimalarial s become more frequent.