AN UNUSUAL TRANSLOCATION BETWEEN 12TEL AND 14Q11 IN A LARGE KINDRED

Citation
S. Palanduz et al., AN UNUSUAL TRANSLOCATION BETWEEN 12TEL AND 14Q11 IN A LARGE KINDRED, Hereditas, 128(3), 1998, pp. 231-234
Citations number
8
Categorie Soggetti
Genetics & Heredity
Journal title
ISSN journal
00180661
Volume
128
Issue
3
Year of publication
1998
Pages
231 - 234
Database
ISI
SICI code
0018-0661(1998)128:3<231:AUTB1A>2.0.ZU;2-I
Abstract
In one couple investigated because of recurrent abortions, the female was found to have an unusual translocation between the long arm of the telomeric region of chromosome 12 and the long arm of the chromosome 14 at band q11. We studied ten additional members of the family who we re under the risk: of the same chromosomal rearrangement, and four of them were found to be carriers. The diagnosis of this translocation wa s determined using different banding techniques and FISH. The karyotyp e was found to be 45,XX,t(12;14)(qtel;q11).