REACTION OF BETA-FLUOROVINAMIDINIUM SALT WITH GRIGNARD-REAGENTS - FACILE AND EFFICIENT ROUTE TO (Z)-ALPHA-FLUORO-ALPHA,BETA-UNSATURATED ALDEHYDES

Authors
YAMANAKA H ODANI Y ISHIHARA T GUPTON JT
Citation
H. Yamanaka et al., REACTION OF BETA-FLUOROVINAMIDINIUM SALT WITH GRIGNARD-REAGENTS - FACILE AND EFFICIENT ROUTE TO (Z)-ALPHA-FLUORO-ALPHA,BETA-UNSATURATED ALDEHYDES, Tetrahedron letters, 39(38), 1998, pp. 6943-6946
Citations number
23
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Tetrahedron letters → ACNP
ISSN journal
00404039
Volume
39
Issue
38
Year of publication
1998
Pages
6943 - 6946
Database
ISI
SICI code
0040-4039(1998)39:38<6943:ROBSWG>2.0.ZU;2-E
Abstract
beta-Fluorovinamidinium salt (1) reacted cleanly with a variety of Gri gnard reagents in tetrahydrofuran at room temperature, followed by aci d workup, to produce the corresponding (Z)-alpha-fluoro-alpha, beta-un saturated aldehydes (3) in good to excellent yields. (C) 1998 Elsevier Science Ltd. All rights reserved.