THE SYNTHESIS OF 2'-HOMOURIDINE, ITS INCORPORATION INTO A DINUCLEOSIDE MONOPHOSPHATE AND HYDROLYTIC BEHAVIOR OF THE DIMER

Authors
PAVEY JBJ LAWRENCE AJ POTTER AJ COSSTICK R ONEIL IA
Citation
Jbj. Pavey et al., THE SYNTHESIS OF 2'-HOMOURIDINE, ITS INCORPORATION INTO A DINUCLEOSIDE MONOPHOSPHATE AND HYDROLYTIC BEHAVIOR OF THE DIMER, Tetrahedron letters, 39(38), 1998, pp. 6967-6970
Citations number
13
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Tetrahedron letters → ACNP
ISSN journal
00404039
Volume
39
Issue
38
Year of publication
1998
Pages
6967 - 6970
Database
ISI
SICI code
0040-4039(1998)39:38<6967:TSO2II>2.0.ZU;2-Q
Abstract
An efficient route to 2'-homouridine (1), a new nucleoside analogue, i s reported that is based on an ene reaction. This nucleoside has been incorporated into a dinucleoside monophosphate and hydrolytic studies on the dimer show that it does not behave like a ribonucleotide. (C) 1 998 Elsevier Science Ltd. All rights reserved.