A STEREOSELECTIVE SYNTHESIS OF A 2-FUNCTIONALIZED-METHYL-1-BETA-METHYLCARBAPENEM KEY INTERMEDIATE VIA DECARBOXYLATION

Authors
CHOI WB LEE J LYNCH JE VOLANTE RP REIDER PJ REAMER RA
Citation
Wb. Choi et al., A STEREOSELECTIVE SYNTHESIS OF A 2-FUNCTIONALIZED-METHYL-1-BETA-METHYLCARBAPENEM KEY INTERMEDIATE VIA DECARBOXYLATION, Chemical communications, (17), 1998, pp. 1817-1818
Citations number
12
Categorie Soggetti
Chemistry
Journal title
Chemical communications → ACNP
ISSN journal
13597345
Issue
17
Year of publication
1998
Pages
1817 - 1818
Database
ISI
SICI code
1359-7345(1998):17<1817:ASSOA2>2.0.ZU;2-#
Abstract
An efficient synthesis of a key intermediate 2a for the synthesis of 2 -functionalized methyl-1 beta-methylcarbapenem antibiotics 1 has been realized via a stereoselective decarboxylation reaction.