NOVEL INTRAMOLECULAR REARRANGEMENT OF 3-BROMO-3,3-DIFLUOROALANINE SCHIFF-BASES VIA RADICAL IPSO-SUBSTITUTION AT THE AROMATIC RING

Authors
AMII H KONDO S UNEYAMA K
Citation
H. Amii et al., NOVEL INTRAMOLECULAR REARRANGEMENT OF 3-BROMO-3,3-DIFLUOROALANINE SCHIFF-BASES VIA RADICAL IPSO-SUBSTITUTION AT THE AROMATIC RING, Chemical communications, (17), 1998, pp. 1845-1846
Citations number
12
Categorie Soggetti
Chemistry
Journal title
Chemical communications → ACNP
ISSN journal
13597345
Issue
17
Year of publication
1998
Pages
1845 - 1846
Database
ISI
SICI code
1359-7345(1998):17<1845:NIRO3S>2.0.ZU;2-D
Abstract
3-Bromo-3,3-difluoroalanine Schiff bases are synthesized by bromodiflu oromethylation of the corresponding glycine Schiff bases with CF2Br2; their intramolecular rearrangement involving radical ipso-substitution at the aromatic ring of the imine moiety provides 3,3-difluoro-3-aryl propanoates in good yields.