QUANTITATIVE H-1 MRI AND MRS MICROSCOPY OF INDIVIDUAL V79 LUNG-TUMOR SPHEROIDS

In this Communication H-1 MRI and MRS microscopy experiments of indivi dual V79 lung tumor spheroids with diameters between 550 and 650 mu m are reported. The results have been used to determine the T-1, T-2, an d D values as well as the concentrations of water, total choline, crea tine/phosphocreatine, and mobile lipids in the viable rims and in the necrotic centers. (C) 1998 Academic Press.