BACKGROUND: Management of malignant renal tumors involving the inferio
r vena cava (IVC) depends on tumor extension within the cava. METHODS:
Of 295 patients treated for renal cancer, propagation of tumor mass t
hrough the renal vein to IVC was seen in 22 (7%) patients. Cephalad ex
tension of the tumor was suprarenal: infrahepatic in 12, retrohepatic
in 6, and within the right atrium in 4 patients. All patients had radi
cal nephrectomy, cavotomy, and complete resection of tumors except 1 w
ith diffuse peritoneal metastasis. RESULTS: Twenty-one patients had cu
rative resections. No operative deaths and no instances of pulmonary e
mbolism or exsanguination occurred. Seventeen patients were alive at 2
years and 12 at 5 years, resulting in 77% and 55% survival rates, res
pectively. CONCLUSIONS: An aggressive approach for vena cava involveme
nt from malignant renal neoplasms resulted in prevention of tumor embo
lus, minimization of blood loss, and maintenance of venous return to t
he heart. Am J Surg. 1998; 176:137-39. (C) 1998 by Excerpta Medica, In
c.