DETERMINATION AND ESTIMATION OF WATER SOLUBILITIES AND OCTANOL WATER PARTITION-COEFFICIENTS FOR DERIVATES OF BENZANILIDES/

Authors
DAI JY JIN LJ WANG LS ZHANG Z
Citation
Jy. Dai et al., DETERMINATION AND ESTIMATION OF WATER SOLUBILITIES AND OCTANOL WATER PARTITION-COEFFICIENTS FOR DERIVATES OF BENZANILIDES/, Chemosphere (Oxford), 37(8), 1998, pp. 1419-1426
Citations number
12
Categorie Soggetti
Environmental Sciences
Journal title
Chemosphere (Oxford) → ACNP
ISSN journal
00456535
Volume
37
Issue
8
Year of publication
1998
Pages
1419 - 1426
Database
ISI
SICI code
0045-6535(1998)37:8<1419:DAEOWS>2.0.ZU;2-I
Abstract
A shake-flask method was used to determine the water solubilities (Sw) and the octanol/water partition coefficients(Kow) of 14 derivates of benzanilides. The results showed that the octanol/water partition coef ficients were correlated (r= -0.93) with Sw. The linear solvation ener gy relationship(LSER) and molecular connectivity methods have been use d to establish correlation equation successfully. The LSER method was used to predict these partitioning properties more accurately. The est imated values were well fitted with observed ones. (C) 1998 Elsevier S cience Ltd. All rights reserved.