Ka. Morano et al., PROTEIN CHAPERONES AND THE HEAT-SHOCK RESPONSE IN SACCHAROMYCES-CEREVISIAE, CURRENT OPINION IN MICROBIOLOGY, 1(2), 1998, pp. 197-203
Recent studies have shed new light on the complexities of the heat sho
ck response in yeast. Multiple pathways for transcriptional induction
of both classic and novel heat shock proteins are emerging together wi
th a more detailed understanding of the interactions between protein c
haperones and their physiological targets. New roles for heat shock pr
oteins in defense and recovery from the impacts of thermal stress on c
ritical cellular processes have expanded our understanding of these el
aborate and ubiquitous proteins.