The past few years have witnessed considerable progress in molecular a
nd biochemical studies of intracellular trafficking in malaria-infecte
d red cells. Highlights include the identification of solute channels
in the vacuolar membrane and the red blood cell membrane, a tubovesicu
lar membrane network that delivers exogenous nutrients and drugs to th
e parasite, and parasite gene families that mediate adherence to endot
helial cells and red cells.