SYNTHESIS OF NOVEL STEROIDAL INHIBITORS OF HIV-1 PROTEASE

Authors
HARBURN JJ LOFTUS GC MARPLES BA
Citation
Jj. Harburn et al., SYNTHESIS OF NOVEL STEROIDAL INHIBITORS OF HIV-1 PROTEASE, Tetrahedron, 54(39), 1998, pp. 11907-11924
Citations number
43
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Tetrahedron → ACNP
ISSN journal
00404020
Volume
54
Issue
39
Year of publication
1998
Pages
11907 - 11924
Database
ISI
SICI code
0040-4020(1998)54:39<11907:SONSIO>2.0.ZU;2-I
Abstract
The design and synthesis of potential steroidal HIV-1 protease inhibit ors is described. Compounds derived from 11-amino-12-keto-cholanic aci d derivatives show modest activity. (C) 1998 Elsevier Science Ltd. All rights reserved.