EFFICACY AND POSSIBLE MECHANISMS OF THE CHINESE HERBS SUCHING-HUO-HSUEI-TANG IN THE TREATMENT OF ADJUVANT-INDUCED ARTHRITIS IN RATS

Authors
CHOU CT WU WL CHANG ML CHANG DM
Citation
Ct. Chou et al., EFFICACY AND POSSIBLE MECHANISMS OF THE CHINESE HERBS SUCHING-HUO-HSUEI-TANG IN THE TREATMENT OF ADJUVANT-INDUCED ARTHRITIS IN RATS, The American journal of Chinese medicine, 21(2), 1993, pp. 159-170
Citations number
NO
Categorie Soggetti
Medicine, General & Internal
Journal title
The American journal of Chinese medicine → ACNP
ISSN journal
0192415X
Volume
21
Issue
2
Year of publication
1993
Pages
159 - 170
Database
ISI
SICI code
0192-415X(1993)21:2<159:EAPMOT>2.0.ZU;2-U
Abstract
The Chinese herbal formula Suching-huo-hsuei-tang (SHT) was studied to evaluate its efficacy and possible mechanism on adjuvant - induced ar thritis (AIA) in rats. SHT was extracted with water, butanol and chlor oform into 5 different layers. The top 3 layers of SHT showed a signif icant suppression of AIA and writhing reaction; the top 2 layers suppr essed neutrophil chemotaxis and platelet aggregation. The results sugg est that SHT is very promising in the treatment of rheumatoid arthriti s (RA) by way of its anti-inflammatory and analgesic action. The possi ble mechanisms for arthritis are multifactorial.