SPONTANEOUS ABNORMAL INVOLUNTARY MOVEMENTS IN FIRST-EPISODE SCHIZOPHRENIA AND SCHIZOPHRENIFORM DISORDER - BASE-LINE RATE IN A GROUP OF PATIENTS FROM AN IRISH CATCHMENT-AREA
M. Gervin et al., SPONTANEOUS ABNORMAL INVOLUNTARY MOVEMENTS IN FIRST-EPISODE SCHIZOPHRENIA AND SCHIZOPHRENIFORM DISORDER - BASE-LINE RATE IN A GROUP OF PATIENTS FROM AN IRISH CATCHMENT-AREA, The American journal of psychiatry, 155(9), 1998, pp. 1202-1206
Objective: This study investigated the rate of spontaneous abnormal in
voluntary movements in a group of patients presenting with a first epi
sode of schizophrenia or schizophreniform psychosis. Method: Seventy-n
ine patients with a first episode of schizophrenia or schizophreniform
psychosis who presented to a catchment area psychiatric service over
a 3-year period, and who were neuroleptic-naive or had been medicated
for less than 1 month, were examined for the presence of involuntary m
ovements with use of the Abnormal involuntary Movement Scale. Results:
Six patients (7.6%) had spontaneous dyskinesia as defined by the crit
eria of Schooler and Kane, and nine other patients had mild orofacial
involuntary movements. The patients with spontaneous dyskinesia had co
mpleted significantly fewer years of education than the patients witho
ut dyskinesia. Spontaneous involuntary movements were unrelated to age
at presentation for treatment. Conclusions: Spontaneous abnormal invo
luntary movements were evident among a proportion of patients with fir
st-episode schizophrenia or schizophreniform psychosis at baseline pre
sentation and were associated with reduced educational attainment. Thi
s finding supports previous suggestions that abnormal involuntary move
ments in schizophrenia may be related to the pathophysiology of the il
lness and therefore cannot: be attributed entirely to the adverse effe
cts of neuroleptic medication.