DETECTION OF THYMINE[2- SELECTIVE REACTION OF KMNO4(2]PHOTODIMER REPAIR IN DNA )

Authors
RAMAIAH D KOCH T ORUM H SCHUSTER GB
Citation
D. Ramaiah et al., DETECTION OF THYMINE[2- SELECTIVE REACTION OF KMNO4(2]PHOTODIMER REPAIR IN DNA ), Nucleic acids research, 26(17), 1998, pp. 3940-3943
Citations number
25
Categorie Soggetti
Biology
Journal title
Nucleic acids research → ACNP
ISSN journal
03051048
Volume
26
Issue
17
Year of publication
1998
Pages
3940 - 3943
Database
ISI
SICI code
0305-1048(1998)26:17<3940:DOTSRO>2.0.ZU;2-1
Abstract
The specific reaction of potassium permanganate with thymine in single -stranded DNA was employed to analyze thymine [2+2] dimer repair in DN A and in DNA/peptide nucleic acid hybrid duplexes. This simple and hig hly sensitive chemical assay is convenient for monitoring repair of th ymine dimers in oligonucleotides.