Background. Neonatologists are criticized for overtreating extremely p
remature infants who die despite invasive and costly care. Withholding
resuscitation at delivery has been recommended as a way to minimize o
vertreatment. It is not known how decisions to forgo initiating aggres
sive care are made, or whether this strategy effectively decreases ove
rtreatment. Objective. To identify whether physicians' or parents' pre
ferences primarily determine the amount of treatment provided at deliv
ery, to examine factors associated with the provision of resuscitation
, and to assess whether resuscitation at delivery significantly postpo
nes death in nonsurvivors. Methods. We evaluated delivery room resusci
tation decisions and mortality for all infants born at 23 to 26 weeks
gestation at the University of North Carolina Hospitals from November
1994 to October 1995. On the day of delivery, the attending neonatolog
ist completed a questionnaire regarding discussion with the parents be
fore delivery, the prognosis for survival estimated before delivery, t
he degree of certainty about the prognosis, parents' preference for th
e amount of treatment at delivery, and the degree of influence exerted
by parents and physicians on the amount of delivery room treatment pr
ovided. Medical records were reviewed for demographics and hospital co
urse. Results. Thirty-one of 41 infants were resuscitated (intubation
and/or cardiopulmonary resuscitation) at delivery. Resuscitation corre
lated with increasing gestational age, higher birth weight, estimated
prognosis for survival greater than or equal to 10%, and uncertainty a
bout prognostic accuracy. Physicians saw themselves as primarily respo
nsible for delivery room resuscitation decisions when the parents' wis
hes about initiating care were unknown, and as equal partners with par
ents when they agreed on the level of care. When disagreement existed,
doctors always thought parents preferred more aggressive resuscitatio
n, and identified parents as responsible for the increased amount of t
reatment at delivery. Twenty-four infants died before hospital dischar
ge. The median age at death was 2 days when physicians primarily deter
mined the amount of treatment at delivery, 1 day when parents primaril
y determined the amount of treatment, and <1 day when responsibility w
as shared equally. The median age at death was <1 day when physicians
and parents agreed about the preferred amount of treatment at delivery
and 1.5 days when they disagreed. The median age at death was <1 day
when parents' preferences were known before delivery and 4 days when p
arents' preferences were unknown. Conclusions. Physicians resuscitated
extremely premature infants at delivery when they were very uncertain
about an infant's prognosis or when the parents' desires about treatm
ent were unknown. When parents' preferences were known, parents usuall
y determined the amount of treatment provided at delivery. Resuscitati
on at delivery usually postponed death by only a few days, decreasing
prognostic uncertainty and honoring what physicians perceived were par
ents' wishes for care, without substantially contributing to overtreat
ment.