THE IMPROVED SYNTHESIS OF ENANTIOPURE (S)-N-ARYLMETHYL-5-OXOPROLINES

Authors
MARCHALIN S KADLECIKOVA K BAR N DECROIX B
Citation
S. Marchalin et al., THE IMPROVED SYNTHESIS OF ENANTIOPURE (S)-N-ARYLMETHYL-5-OXOPROLINES, Synthetic communications, 28(19), 1998, pp. 3619-3624
Citations number
12
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Synthetic communications → ACNP
ISSN journal
00397911
Volume
28
Issue
19
Year of publication
1998
Pages
3619 - 3624
Database
ISI
SICI code
0039-7911(1998)28:19<3619:TISOE(>2.0.ZU;2-8
Abstract
A mild procedure for the preparation of enantiopure N-alkylated (S)-()-5-oxoprolines 3a-r is described. The method starting from (S)-glutam ic acid appears generally applicable to substrates with a wide range o f substituents.