It is possible to minimise the invasiveness of diagnosis in cases of p
athological nipple secretion by examining the lactiferous duct using m
icrofibre optics. In this study, the visualisation of the internal lac
tiferous duct was tested on an animal model and in humans. Flexible fi
bre-endoscopes, with diameters of 0.50 and 0.75 mm (3000 and 6000 pixe
l), and a semi-rigid fibre-endoscope with a diameter of 0.85 mm (6000
pixel) were tested in conjunction with Teflon catheters and rigid stee
l microtrocars of 0.8, 1.1 and 1.2 mm outer diameter. The lactiferous
duct system could be visualised reproducibly from the orificium of the
ductus mamillaris over all its ramifications to its endings in comple
te expansion.