In three cases of primary pulmonary amyloidosis the chief complaint wa
s hemosputum. The diagnosis of amyloidosis was made using histochemica
l analysis of bronchial wall biopsy in all cases; multiple nodular les
ions were observed in trachea and bronchi on flexible fiberoptic bronc
hoscopy, The surface of the tracheobronchial mucosa was smooth but ble
d easily. In one patient, chest X-ray film showed a solitary nodular s
hadow in the left lower lung field. These three cases were tracheobron
chial amyloidosis, and one case was combined with nodular parenchymal
type amyloidosis.