CONTROL OF CANDIDA-ALBICANS MURINE VAGINITIS BY TOPICAL ADMINISTRATION OF POLYCARBOPHIL-ECONAZOLE COMPLEX

Authors
GHELARDI E TAVANTI A LUPETTI A CELANDRONI F BOLDRINI E CAMPA M SENESI S
Citation
E. Ghelardi et al., CONTROL OF CANDIDA-ALBICANS MURINE VAGINITIS BY TOPICAL ADMINISTRATION OF POLYCARBOPHIL-ECONAZOLE COMPLEX, Antimicrobial agents and chemotherapy, 42(9), 1998, pp. 2434-2436
Citations number
22
Categorie Soggetti
Pharmacology & Pharmacy",Microbiology
Journal title
Antimicrobial agents and chemotherapy → ACNP
ISSN journal
00664804
Volume
42
Issue
9
Year of publication
1998
Pages
2434 - 2436
Database
ISI
SICI code
0066-4804(1998)42:9<2434:COCMVB>2.0.ZU;2-#
Abstract
The complexation of econazole with the mucoadhesive polycarbophil was found to significantly improve the therapeutic benefit of the drug in the topical treatment of experimental vaginal candidiasis in mice, whi le no difference in the antimycotic activity exerted by econazole and polycarbophil econazole could be detected in vitro.