ACTIVITIES OF GATIFLOXACIN COMPARED TO THOSE OF 7 OTHER AGENTS AGAINST ANAEROBIC ORGANISMS

The agar dilution MIC was used to compare activities of gatifloxacin w ith those of ciprofloxacin, sparfloxacin, trovafloxacin, ampicillin, a mpicillin-sulbactam, clindamycin, and metronidazole against 351 anaero bes. Overall MICs at which 50% of the isolates are inhibited and MICs at which 90% of the isolates are inhibited (in micrograms per millilit er) were as follows: gatifloxacin, 0.5 and 4; ciprofloxacin, 2 and 32; sparfloxacin, 2 and 8; trovafloxacin, 1 and 4; ampicillin, 1 and 64; ampicillin-sulbactam, 0.5 and 4; clindamycin, 0.125 and 8; and metroni dazole, 1 and >16, respectively. Gatifloxacin MICs were similar to tho se of trovafloxacin in ail organism groups.