K. Hirayama et al., SYNTHESIS OF POLYMER-COATED SILICA PARTICLES WITH SPECIFIC RECOGNITION SITES FOR GLUCOSE-OXIDASE BY THE MOLECULAR IMPRINTING TECHNIQUE, Chemistry Letters, (8), 1998, pp. 731-732
A polymer layer around silica beads, composed of acrylamide, acrylic a
cid, and crosslinkers, was able to preferentially recognize glucose ox
idase (GOD) from a mixture of proteins. Matching between the zeta-pote
ntial of GOD and that of its imprinted polymer is suggested to be impo
rtant in enhancing the recognition effect.