INHIBITION OF LYMPHOPROLIFERATIVE RESPONSE AND ITS RESTORATION WITH AGLUCAN IMMUNOMODULATOR IN MICE WITH EXPERIMENTAL LARVAL TOXOCAROSIS

Authors
BOROSKOVA Z REITEROVA K DUBINSKY P TOMASOVICOVA O MACHNICKA B
Citation
Z. Boroskova et al., INHIBITION OF LYMPHOPROLIFERATIVE RESPONSE AND ITS RESTORATION WITH AGLUCAN IMMUNOMODULATOR IN MICE WITH EXPERIMENTAL LARVAL TOXOCAROSIS, Folia microbiologica, 43(5), 1998, pp. 475-476
Citations number
7
Categorie Soggetti
Microbiology,"Biothechnology & Applied Migrobiology
Journal title
Folia microbiologica → ACNP
ISSN journal
00155632
Volume
43
Issue
5
Year of publication
1998
Pages
475 - 476
Database
ISI
SICI code
0015-5632(1998)43:5<475:IOLRAI>2.0.ZU;2-K
Abstract
A high infective dose of Toxocara canis eggs (2 500 eggs per mouse) in duced a partial immunosuppression in mice, manifested by inhibition of the proliferative response of splenic T and B cells to polyclonal act ivators. A glucan immunomodulator given to infected animals at the beg inning of the experiment showed a marked stimulative and restorative e ffect on the parasite-suppressed lymphoproliferative response. The abi lity of T. canis to migrate in the host was reduced in glucan-treated animals by 27 %.