THE TREATMENT OF NEPHROTIC SYNDROME CAUSED BY PRIMARY (LIGHT-CHAIN) AMYLOID WITH VINCRISTINE, DOXORUBICIN AND DEXAMETHASONE

Authors
WARDLEY AM JAYSON GC GOLDSMITH DJA VENNING MC ACKRILL P SCARFFE JH
Citation
Am. Wardley et al., THE TREATMENT OF NEPHROTIC SYNDROME CAUSED BY PRIMARY (LIGHT-CHAIN) AMYLOID WITH VINCRISTINE, DOXORUBICIN AND DEXAMETHASONE, British Journal of Cancer, 78(6), 1998, pp. 774-776
Citations number
19
Categorie Soggetti
Oncology
Journal title
British Journal of Cancer → ACNP
ISSN journal
00070920
Volume
78
Issue
6
Year of publication
1998
Pages
774 - 776
Database
ISI
SICI code
0007-0920(1998)78:6<774:TTONSC>2.0.ZU;2-Z
Abstract
Three out of four patients with primary (light chain) amyloid nephroti c syndrome treated with vincristine, doxorubicin and dexamethasone (VA D) induction obtained a partial response and are alive in continuing r emission at 4.1, 6.5 and 9.3 years. These preliminary results are of c onsiderable interest and suggest that prospective evaluation of this r egimen is warranted in patients with this condition.