MAXIMUM-ENTROPY CHROMATOGRAM RECONSTRUCTION

Maximum entropy has been successfully applied to problems of optical i mages and NMR spectroscopy. In this paper, we present the results of m aximum entropy deconvolution applied to simulated and real chromatogra phic data. A brief theoretical discussion is given. The technique is t ested both qualitatively and quantitatively using simulated data. Peak resolution can be dramatically improved but quantitative accuracy is limited. The technique is applied to a re-analysis of Pioneer Venus ch romatographic data and to storage column data. (C) 1998 Elsevier Scien ce B.V. All rights reserved.