IDIOPATHIC NONOBSTRUCTIVE HYPERTROPHIC CARDIOMYOPATHY, VITAMIN-B-12 DEFICIENCY AND GASTRIC ADENOCARCINOMA - AN UNREPORTED ASSOCIATION IN A TEENAGER

Citation
B. Wolach et al., IDIOPATHIC NONOBSTRUCTIVE HYPERTROPHIC CARDIOMYOPATHY, VITAMIN-B-12 DEFICIENCY AND GASTRIC ADENOCARCINOMA - AN UNREPORTED ASSOCIATION IN A TEENAGER, European journal of pediatrics, 157(9), 1998, pp. 715-718
Citations number
19
Categorie Soggetti
Pediatrics
ISSN journal
03406199
Volume
157
Issue
9
Year of publication
1998
Pages
715 - 718
Database
ISI
SICI code
0340-6199(1998)157:9<715:INHCVD>2.0.ZU;2-#
Abstract
A 14-year-old boy presented with anorexia and weakness whereon the dia gnosis of dimorphic anaemia was made. An excellent response to iron an d vitamin B-12 was observed. In addition, the patient had non-obstruct ive hypertrophic cardiomyopathy. At endoscopy 2.5 years later, an aden ocarcinoma was diagnosed and the patient underwent a high subtotal gas trectomy. To the best of our knowledge, this rare association has neve r been reported in children. Conclusion We report a youngster with per nicious anaemia, associated with non-obstructive hypertrophic cardiomy opathy in whom gastric adenocarcinoma was found. Patients with pernici ous anaemia are at greater risk of developing gastric carcinoma than t he general population, therefore we recommend routine periodic gastros copic surveillance in the paediatric population with pernicious anaemi a.