An unusual case of infantile myofibromatosis of the solitary type occu
rring in an intracranial location in a 48-day-old female infant is pre
sented. To our knowledge, there are no other descriptions in the liter
ature of infantile myofibromatosis with exclusively intracranial invol
vement. The immunohistochemical and electron microscopic findings conf
irm the myofibroblastic origin of the proliferation.