Ca. Calvert et al., THYROID-STIMULATING HORMONE STIMULATION TESTS IN CARDIOMYOPATHIC DOBERMAN-PINSCHERS - A RETROSPECTIVE STUDY, Journal of veterinary internal medicine, 12(5), 1998, pp. 343-348
Thyroid-stimulating hormone (TSH) response tests were performed in 152
Doberman Pinschers. Seventy-nine dogs had cardiomyopathy (46 were in
congestive heart failure [CHF] and 33 were not in CHF). Seventy-three
dogs were presented for noncardiac problems (15 with skin disease, 21
with neurologic disease, 20 with internal medicine disorders, and 17 w
ith other problems), although some may have had cardiomyopathy. The TS
H response test results in the cardiomyopathic group were interpreted
as normal or euthyroid-sick in 45 (57%) dogs, abnormal in 23 (29%) dog
s, and equivocal in 11 (14%) dogs. The prevalence of hypothyroidism in
the CHF and non-CHF cardiomyopathy groups was nor different. Among th
e dogs presented for noncardiac problems, 27 (37%) were assessed as no
rmal or euthyroid-sick 29 (40%) as hypothyroid, and 17 (23%) as equivo
cal. No significant differences were found in the prevalence of hypoth
yroid test results among the subgroups of these dogs. The prevalence o
f hypothyroidism was not higher in the cardiomyopathic group compared
to the other group, and 63 and 49% of cardiomyopathic dogs with or wit
hout CHE respectively, tested as either euthyroid or euthyroid-sick.