CONVENIENT SYNTHESES OF 2-ALKYL(ARYL)-4,5-DIPHENYLOXAZOLES AND 2-ALKYL(ARYL)-4-PHENYLOXAZOLES

Authors
PEI WW LI SH NIE XP LI YW PEI J CHEN BZ WU J YE XL
Citation
Ww. Pei et al., CONVENIENT SYNTHESES OF 2-ALKYL(ARYL)-4,5-DIPHENYLOXAZOLES AND 2-ALKYL(ARYL)-4-PHENYLOXAZOLES, Synthesis, (9), 1998, pp. 1298-1304
Citations number
31
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Synthesis → ACNP
ISSN journal
00397881
Issue
9
Year of publication
1998
Pages
1298 - 1304
Database
ISI
SICI code
0039-7881(1998):9<1298:CSO2A2>2.0.ZU;2-6
Abstract
The synthetic methods to prepare 2-alkyl(aryl)-4,5-diphenyloxazoles an d 2-alkyl(aryl)-4-phenyloxazoles were improved on the basis of a mecha nistic study of oxazole formation from alpha-hydroxy ketones (carboxyl ic esters of benzoin and phenacyl alcohols). By these methods, seven t risubstituted oxazoles and twelve disubstituted oxazoles of the title compounds were prepared.