This paper presents a descriptive analysis of 501 cases of laryngeal c
ancer. The patients were classified according to their age, sex, prima
ry tumour localisation and stage. There were 448 males and 53 females,
with a male-to-female ratio of 8.5:1. The peak incidence of cancer wa
s detected in the 6th and 7th decades of age. The most common primary
tumour localisation was the glottis. Three-hundred-and-forty patients
presented at advanced tumour stages (T3/T4). The proportion of patient
s presenting matastatic neck nodes was 29.3% and the incidence of meta
static lymph nodes increased with increasing T stage. Histopathologica
l analysis revealed that 98% of tumours were squamous cell carcinomas.
There were 125 well-differentiated, 235 moderately differentiated and
133 poorly differentiated carcinomas. Among other tumours, there was
1 adenoid squamous cell carcinoma, 1 giant cell carcinoma, 1 adenoma p
leomorphicum, I adenoid cystic carcinoma (cylindroma), 1 haemangioperi
cytoma, 1 verrucous cell carcinoma, 1 lymphoepithelioma and 1 granular
cell tumour. (C) 1998 Elsevier Science Ltd. All rights reserved.