D. Jancura et al., SURFACE-ENHANCED RESONANCE RAMAN-SPECTROSCOPY OF HYPOCRELLIN-A - AN EFFECT OF EXCITATION WAVELENGTH AND PH, SPECT ACT A, 54(10), 1998, pp. 1519-1526
Citations number
32
Categorie Soggetti
Spectroscopy
Journal title
SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY
Surface-enhanced Raman (SERS) and surface-enhanced resonance Raman spe
ctroscopy (SERRS) of hypocrellin A, a photoactive antiviral and antine
oplastic agent, are reported for the first time on aqueous silver coll
oid. An analysis of the excitation and pH dependent SERRS spectra of h
ypocrellin leads to: (i) the interpretation of the main vibrational mo
des of hypocrellin; (ii) the determination of hypocrellin SERRS marker
bands for the carbonyl group protonation; and (iii) a conclusion abou
t similar character of region where intramolecular hydrogen bond betwe
en quinoid carbonyl group and adjacent hydroxyl group is formed in hyp
ocrellin with that of the structurally related phenanthro-perylen mole
cule, hypericin. (C) 1998 Elsevier Science B.V. All rights reserved.