PROPYLENE SPACED ALLYL TIN REAGENTS - A NEW CLASS OF FLUOROUS TIN REAGENTS FOR ALLYLATIONS UNDER RADICAL AND METAL-CATALYZED CONDITIONS

Authors
CURRAN DP LUO ZY DEGENKOLB P
Citation
Dp. Curran et al., PROPYLENE SPACED ALLYL TIN REAGENTS - A NEW CLASS OF FLUOROUS TIN REAGENTS FOR ALLYLATIONS UNDER RADICAL AND METAL-CATALYZED CONDITIONS, Bioorganic & medicinal chemistry letters, 8(17), 1998, pp. 2403-2408
Citations number
35
Categorie Soggetti
Chemistry Inorganic & Nuclear","Chemistry Medicinal
Journal title
Bioorganic & medicinal chemistry letters → ACNP
ISSN journal
0960894X
Volume
8
Issue
17
Year of publication
1998
Pages
2403 - 2408
Database
ISI
SICI code
0960-894X(1998)8:17<2403:PSATR->2.0.ZU;2-O
Abstract
A new generation of propylene-spaced fluorous allyltin reagents [(Rf(C H2)(3))(3)SnCH2CH=CH2] is described. These succeed in radical allylati ons where their lower homologs (ethylene-spaced) fail, and they provid e improved performance in transition metal catalyzed allylations. The reagents and byproducts are readily separated by simple fluorous-organ ic liquid-liquid or solid-liquid extractions. (C) 1998 Elsevier Scienc e Ltd. All rights reserved.