TOXICITY OF ALTERNATIVES TO CHLOROFLUOROCARBONS - HFC-134A AND HCFC-123

The following is a summary of the National Research Council/National A cademy of Sciences report entitled Toxicity of Alternatives to Chlorof luorocarbons: HFC-134a and HCFC-123. That report was prepared in respo nse to a request from the U.S. Navy to review the toxicity data on the se chlorofluorocarbon (CFC) substitutes and determine the scientific v alidity of emergency exposure guidance levels (EEGLs) for 1 and 24 h a nd continuous exposure guidance levels (CEGLs) for 90 days. These expo sure limits are for use in nuclear submarines. The report was prepared by the National Research Council Subcommittee to Review Toxicity of A lternatives to Chlorofluorocarbons. The rosier of the subcommittee is as follows.