DETERMINATION OF ACETYLSALICYLIC-ACID IN TABLETS WITH SALICYLATE ION-SELECTIVE ELECTRODE IN A BATCH INJECTION-ANALYSIS SYSTEM

Authors
FERNANDES JCB GARCIA CB GRANDIN LA NETO GD GODINHO OES
Citation
Jcb. Fernandes et al., DETERMINATION OF ACETYLSALICYLIC-ACID IN TABLETS WITH SALICYLATE ION-SELECTIVE ELECTRODE IN A BATCH INJECTION-ANALYSIS SYSTEM, Journal of the Brazilian Chemical Society, 9(3), 1998, pp. 249-251
Citations number
13
Categorie Soggetti
Chemistry
Journal title
Journal of the Brazilian Chemical Society → ACNP
ISSN journal
01035053
Volume
9
Issue
3
Year of publication
1998
Pages
249 - 251
Database
ISI
SICI code
0103-5053(1998)9:3<249:DOAITW>2.0.ZU;2-L
Abstract
The feasibility of the use of a Batch Injection Analysis (BIA) system for potentiometric determination of acetylsalicylic acid in tablets, w ith a membrane ion selective electrode, was investigated. There is no significant difference between the results obtained by the proposed me thod(12) at the 95% confidence level. and those obtained by the Standa rd British Pharmacopaeia method Values of 4% and 2.5% for R.S.D. were obtained by the application of the BIA-potentiometric method and for t he injections respectively. About 90 determinations per hour can be pe rformed with the proposed BIA potentiometric method.