Jcb. Fernandes et al., DETERMINATION OF ACETYLSALICYLIC-ACID IN TABLETS WITH SALICYLATE ION-SELECTIVE ELECTRODE IN A BATCH INJECTION-ANALYSIS SYSTEM, Journal of the Brazilian Chemical Society, 9(3), 1998, pp. 249-251
The feasibility of the use of a Batch Injection Analysis (BIA) system
for potentiometric determination of acetylsalicylic acid in tablets, w
ith a membrane ion selective electrode, was investigated. There is no
significant difference between the results obtained by the proposed me
thod(12) at the 95% confidence level. and those obtained by the Standa
rd British Pharmacopaeia method Values of 4% and 2.5% for R.S.D. were
obtained by the application of the BIA-potentiometric method and for t
he injections respectively. About 90 determinations per hour can be pe
rformed with the proposed BIA potentiometric method.