AN ULTRASTRUCTURAL-STUDY OF THE PHAGOCYTOSIS OF BURKHOLDERIA-PSEUDOMALLEI

Authors
HARLEY VS DANCE DAB TOVEY G MCCROSSAN MV DRASAR BS
Citation
Vs. Harley et al., AN ULTRASTRUCTURAL-STUDY OF THE PHAGOCYTOSIS OF BURKHOLDERIA-PSEUDOMALLEI, Microbios, 94(377), 1998, pp. 35-45
Citations number
14
Categorie Soggetti
Microbiology
Journal title
Microbios → ACNP
ISSN journal
00262633
Volume
94
Issue
377
Year of publication
1998
Pages
35 - 45
Database
ISI
SICI code
0026-2633(1998)94:377<35:AUOTPO>2.0.ZU;2-#
Abstract
Burkholderia pseudomallei causes melioidosis and is believed to be an intracellular pathogen in human and animal disease. The uptake of B. p seudomallei by mouse peritoneal macrophages and cells in tissue cultur e was examined by electron microscopy. In all the systems studied B. p seudomallei were phagocytosed and apparently inhibited the normal proc esses of intracellular killing. Destruction of the phagosome membrane occurred and the bacteria escaped into the cytoplasm.