1,2,4-TRIAZINE N-OXIDES AND THEIR ANNELATED DERIVATIVES

Review deals with synthesis and properties of 1,2,4-triazine N-oxides and their annelated derivatives. Methods for introduction of N-oxide g roups into 1,2,4-triazine ring by direct oxidation as well as cyclisat ion with participation of nitro, nitroso and isonitroso groups are sur veyed. Interaction of 1,2,4-triazine N-oxides with electrophiles, nucl eophiles and dienophiles is discussed. Effect of N-oxide group on chem ical shifts in NMR H-1,C-13, N-15 spectra and features of 1,2,4-triazi ne N-oxides decomposition in mass spectra are analysed.