Age-related changes in the nervous system may present with physical si
gns that are not unlike early manifestations of several clinical disor
ders. Gait disturbances (immobility), balance difficulties (instabilit
y), and certain motor control problems tie, tremor) are not necessaril
y signs of a disease state. The clinician needs to be reminded that mo
st I physiologic functions decline at a rate of 1% per year, beginning
at age 30 Often compounding ''natural'' decline are the motor problem
s related to disuse. This is especially true for the inactive individu
al suffering from depression, cardiac or pulmonary insufficiency, pain
ful joint and muscle conditions, substance abuse and, sometimes, simpl
y social isolation.