G. Bossi et al., THYROID VOLUME IS PROGRESSIVELY REDUCED AS A SEQUELA OF NECK IRRADIATION FOR CHILDHOOD HODGKINS-DISEASE, Haematologica, 83(8), 1998, pp. 754-756
Thyroid volume reduction was observed, among 25 subjects off-therapy a
fter Hodgkin's disease. The volume reduction was related to dose (p=0.
014) and time from radiotherapy (p=0.01). The correlation was very spe
cific since all patients with reduced volume had hypothyroidism, but n
ot very sensitive since 25% of subjects with thyroid dysfunction had n
ormal gland volume.