K. Krishnankutty et P. Venugopalan, METAL-CHELATES OF CURCUMINOIDS, Synthesis and reactivity in inorganic and metal-organic chemistry, 28(8), 1998, pp. 1313-1325
Curcuminoids, a group of structurally related 1,3-dicarbonyl compounds
, are the most important physiologically active components present in
the traditional herbaceous medicinal plant oriental turmeric (Curcuma
longa Linn., Zingiberaceae family). Nickel(II), copper(II), zinc(II) a
nd paliadium(II) chelates of synthetic analogues of these 1,7-diaryl-1
,6-heptadiene-3,5-diones have been synthesized. UV, IR, H-1 and C-13 N
MR and mass spectral data of the ML2 complexes clearly indicate that t
he metal ion replaced the enol proton with the formation of a stable s
ix-membered metal chelate ring involving the dicarbonyl function.