HYPERBARIC-OXYGEN IN THE TREATMENT OF REFRACTORY HEMORRHAGIC CYSTITIS

Haemorrhagic cystitis is a common and often debilitating complication of chemotherapy for which treatment is frequently unsatisfactory. With over 80 cases reported of radiation-induced cystitis treated successf ully with hyperbaric oxygen, attention is now turning to the treatment of chemotherapeutic agent-induced cystitis. We report a case of haemo rrhagic cystitis occurring after autologous peripheral blood stem cell transplantation for multiple myeloma. The patient had received cyclop hosphamide and busulfan and had BK and adenoviruria, The haemorrhage w as refractory to multiple conventional treatments but resolved after a course of hyperbaric oxygen.