CT and MR imaging permit exquisite visualization of the complex spatia
l anatomy of the suprahyoid neck. In spite of the large body of litera
ture devoted to these spaces, their names and locations often are diff
icult to learn. By knowing the spaces and their components, the radiol
ogist can generate an anatomically based differential diagnosis. This
article presents a simplified approach to the various spaces of the su
prahyoid neck and their anatomic components. Each space is discussed s
eparately and is accompanied by a table that lists a differential diag
nosis based primarily on the normal anatomic contents of the space.