We have determined the complete nucleotide sequence and the deduced am
ino acid polypeptide sequence of the genome of a dengue-1 (DEN-1) viru
s strain isolated from a patient on Nauru in the Western Pacific in 19
74 (West Pac 74). The complete genome is 10,735 nucleotides in length
and contains a single long open reading frame of 10,176 nucleotides en
coding a polyprotein of 3392 amino acids. When compared to DEN-1 Singa
pore S275/90, the nucleotide and amino acid sequence homology are 94%
and 97.8%, respectively.