BAR-SHAPED NUCLEAR CHROMATIN IN CONJUNCTIVAL SAMPLES - WITH CYTOLOGICFEATURES AND ULTRASTRUCTURAL CORRELATION

OBJECTIVE: To study the cytomorphologic features of bar-shaped chromat in in conjunctival samples and assess logic similarities between nucle ar grooves seen in thyroid papillary carcinoma and bar-shaped chromati n. STUDY DESIGN: A total of 10 conjunctival samples from five voluntee rs were studied cytologically. Of the 10 samples, 2 showed bar-shaped chromatin. This chromatin was studied using a light microscope, scanni ng electron microscope (SEM) and transmission electron microscope (TEM ). RESULTS: On SEM, bar-shaped chromatin tons ob shaped chromatin exis ted both in the center of the nuclei and in the nuclear membrane and c ytoplasm. It was surrounded by outer and inner membranes. CONCLUSION: It seems that bar-shaped chromatin is formed by the nuclear membrane a nd that these changes are essentially the same configuration as cytopl asmic invaginations commonly present ii? papillary carcinoma of the th yroid.