P. Bertus et P. Pale, SYNTHESIS OF ENYNES AND EPOXYENYNES BY COUPLING - USE OF A NEW SET OFCATALYSTS BASED ON PD-AG SALTS, Journal of organometallic chemistry, 567(1-2), 1998, pp. 173-180
The new couple of catalysts Pd(PPh3)(4) and AgI are very efficient for
the coupling of vinyltriflates and terminal alkynes in the presence o
f a bulky amine in dimethylformamide at room temperature. Enynes and e
poxyenynes are obtained in good to excellent yields. As illustrated wi
th several examples, a wide variety of functional groups are well tole
rated in the described conditions. Silver acetylides have been propose
d as intermediate in this reaction. (C) 1998 Elsevier Science S.A. All
rights reserved.