Background When severe symptoms of solitary rectal ulcer syndrome pers
ist despite medical management, surgery may be necessary. Methods A re
trospective review was carried out of 81 patients undergoing surgery f
or solitary rectal ulcer syndrome in the 10-year period from 1984 to 1
993 to determine the long-term outcome at a minimum follow-up of 12 mo
nths. Of the 81 patients, 15 were excluded from further analysis (11 w
ere followed up for less than 12 months, two died and two were lost to
follow-up). Sixty-six patients were studied (median age 38 (range 15-
77) years; 53 female). Of these, 49 underwent rectopexy, nine Delorme'
s operation, two anterior resection and four creation of a stoma as th
e initial operation. Results At a median follow-up of 90 (range 12-177
) months, the rectopexy had failed in 22 of 49 patients; 19 of these p
atients underwent further surgery, including rectal resection with col
oanal anastomosis (four with three failures), colostomy (11) and other
procedures (four). Ultimately, 14 required a stoma. Constipation was
the indication for a stoma in nine of the 11 patients who had colostom
y as the first procedure after failure of rectopexy. Nine patients had
Delorme's operation as the first procedure. At median follow-up of 38
(range 19-107) months, there were four failures. Two of these ultimat
ely required a stoma. Of the seven patients who underwent anterior res
ection as the initial or subsequent procedure, a stoma was finally nec
essary in four. Anterior resection used as a salvage procedure was not
successful. The overall stoma rate was 30 per cent (20 patients). Of
11 symptoms assessed before operation only incontinence and incomplete
evacuation were related to a poor outcome following surgery. Conclusi
on Antiprolapse operations result in a satisfactory long-term outcome
in about 55-60 per cent of patients having surgery for solitary rectal
ulcer syndrome. Results of anterior resection are disappointing.