A 33-year-old black woman with an unusual case of a solitary granular
cell tumor (GCT) involving the foe is presented, as is a review of the
literature. The clinical presentation, histopathologic appearance, di
fferential diagnosis, and treatment of solitary granular cell tumors a
re discussed. GCTs are uncommon tumors and are thought to be of Schwan
n cell origin. These tumors usually present as reddish-brown to flesh-
colored papules that are occasionally fender or pruritic, The surface
is usually smooth, but may be ulcerated or verrucous, Although they ar
e usually solitary, they may be multiple. These tumors are almost alwa
ys benign, but malignant variants have been reported. Predilection is
greatest in females, and blacks are affected several times more often
than whites. The skin overlying the face, trunk, fingers, and mucous m
embranes account for the vast majority of reported cases.