Mr. Castine et al., THE ROLE OF LIFE EVENTS IN ONSET AND RECURRENT EPISODES OF SCHIZOPHRENIA AND SCHIZOAFFECTIVE DISORDER, Journal of Psychiatric Research, 32(5), 1998, pp. 283-288
The experience of both positive and negative recent life events has lo
ng been recognized as a possible precipitant of episodes of psychiatri
c illness. Among individuals with recurrent mood disorders, investigat
ors have found that recent life events are more likely to be associate
d with initial and early episodes of illness, with later episodes less
likely to be temporally associated with life events. This study inves
tigated the relationship between recent life events and episodes of il
lness in schizophrenia (defined as the number of acute episodes of sch
izophrenia requiring hospitalization). Among 32 male U.S. Military vet
eran inpatients, those with three or fewer episodes of illness reporte
d significantly more recent life events than those patients with more
than three episodes of illness (P = 0.01). Overall, recent life events
were negatively correlated with number of episodes (P < 0.05). These
data suggest that initial or early episodes of schizophrenic illness a
re more likely to be associated with recent life events than are later
episodes. (C) 1998 Elsevier Science Ltd. All rights reserved.