Objective: This study aimed to report the occurrence of visual field d
efects after pars plana vitrectomy (PPV) for the treatment of each of
the following conditions: macular hole (MH), subretinal neovascular me
mbrane (SRNVM), and epiretinal membrane proliferation (EMP). This stud
y also aimed to speculate on the pathogenic mechanisms for the observe
d field defects. Design: Noncomparative case series. Participants: The
study included 48 subjects (50 eyes). Twenty-one of the 50 eyes had s
tage III MH, 13 eyes had SRNVM, and 16 eyes had EMP. Testing: Goldmann
kinetic perimetry was performed postoperatively. Main Outcome Measure
: Visual field defects. Results: Nine (18%) of the 50 eyes had visual
field defects. Four (19%) of the 21 eyes with MH and 5 (38%) of the 13
eyes with SRNVM had visual field defects. Of the 16 patients who had
epiretinal membrane peeling, none had a visual field defect. An air-fl
uid exchange had been performed in all patients found to have a postvi
trectomy field defect. The difference in rate of visual field defects
in eyes that had air-fluid exchange (EMP group) was statistically sign
ificant (P < 0.05, chi-square), No significant correlation was found b
etween visual field defect and preoperative intraocular pressure, post
operative intraocular pressure, patient's age, and iatrogenic detachme
nt of the vitreous cortex. The field defects identified were altitudin
al (2 eyes), baring of the blind spot (1 eye), inferotemporal (3 eyes)
, inferonasal (2 eyes), and superonasal (1 eye). Conclusions: Central
and peripheral visual field defects may occur after PPV for the treatm
ent of MHs or SRNVMs. Air-fluid exchange procedure was the common deno
minator in all of the patients found to have visual field deficit. The
etiology is likely to be trauma to the optic nerve region during the
air-fluid exchange procedure.