This theoretical paper reviews the status of generalized anxiety disor
der (GAD) and the Axis I and Axis II disorders with which it is often
comorbid. Differences in comorbidity between the epidemiological and c
linical literatures are discussed. Special attention is given to panic
disorder, the symptoms of which are similar to those of GAD. The boun
daries of GAD and its relationship to other Axis I disorders and to Ax
is II disorders raise important implications for its classification.